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Download Citation on ResearchGate | Antibacterial activity of Peganum harmala | Successive petroleum ether, chloroform and methanol extracts of Peganum. Successive petroleum ether, chloroform and methanol extracts of Peganum harmala seeds were tested (in vitro) for their antibacterial activity. examine the antibacterial activities of Peganum harmala extracts on the Key words: Antimicrobial effect, Biofilm, Peganum harmala, Pathogenic bacteria.

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Based on the results from pH treatment Figure 7 Fig. The extract concentrations more than 0.

Purpose The present study compared the antimicrobial activity of ethanolic extract of Peganum harmala L. The authors of this manuscript certify that they have no financial or other competing interest concerning this article.

In conclusion, ethanolic extract of P. Combination of seed atibacterial root extract with novobiocin against E. Unlike the results that are shown in Figures 1 Fig.

Peganum harmala can minimize Escherichia coli infection in poultry, but long-term feeding may induce side effects. It is also reported that ethanolic extract of P. Finally, the result of these treatments was found by measurement of the inhibition zone against one of the most important human pathogenic bacterium. Harmalin is the best-known alkaloid in several researches that was studied.


Antibacterial activity of flower extract of P. Bergey’s manual of systematic bacteriology. Preparation of extract The leaf, flower, seed and stem were hharmala dried at room temperature for ten days while the root was shade dried for twenty days. Synergistic interaction of Helichrysum pedunculatum leaf extracts with antibiotics against wound infection associated bacteria. Results On the basis of antinacterial obtained results that are shown in Figures Fig.

The turbidimetry of the suspension was adjusted to the McFarland 0. The results of the combination of seed and root extracts of P.

Antimicrobial Activity of Peganum Harmala L. on Streptococcus mutans Compared to % Chlorhexidine

Also, all of the avtivity bacteria were resistant to colistin. In evaluating the function of extract sntibacterial more accurate method as micro broth dilution assay, it was observed that the concentrations higher than 5. So far, several alkaloids with pharmaceutical activity including harmine, harmane, harmalol, harmaline, vasicine, vasicinon and peganine have been obtained from the various parts of this plant Fathiazada et al. It’s native to semi-arid rangeland, steppe area and sandy soils Mahmoodian et al.

Antibacterial activity of leaf extract of P. Moreover, MIC values for seed and root extracts against B.

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Viability of Vero cells in different concentrations of ethanolic extract of P. Tested against Gram negative pegabum the obtained results were inconsistent. Reducing dental plaque formation and caries development.


Gram negative bacterial species were Pseudomonas aeruginosa, Brucella melitensisProteus mirabilisSalmonella typhiEscherichia coli and Klebsiella pneumoniae. Iranian J Pharmaceut Sci. Eur J Scientific Res.

The least concentration that inhibited colony formation on agar was considered as MBC for the extract. In general, the obtained results from TLC revealed that these two parts of P. Tested microorganisms A total of thirteen bacteria were selected for this study. A review of current methods and implications for novel pharmaceuticals. Plant regeneration from hypocotyl culture of Peganum harmala. Synergistic effect of seed extract in combination with novobiocin against E.

Pegabum Concentrations of 50, 25, and Alkaloids from the peganumm of Peganum harmala showing antiplasmodial and vasorelaxant activities. The data were analyzed with descriptive methods. Among Gram positive bacteria, S. J Pharm Pharm Sci. Gram positive bacterial species were Bacillus anthracisBacillus cereusBacillus pumilusStaphylococcus aureusStaphylococcus epidermidisListeria monocytogenes and Streptococcus pyogenes.

Antibacterial effect of leaf part was moderate while stem and flower extracts showed relatively poor activity. In this study, ethanol extract of the herb had a greater inhibitory effect than the aqueous extract.

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