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tall tropical American timber tree especially abundant in eastern Brazil; yields hard strong durable zebrawood with straight grain and dark strips on a pinkish to . Gonçalo Alves ou Gonçaleiro (Astronium fraxinifolium) Família Anacardiaceae. Árvore rústica de médio porte, comum em várias regiões, ás vezes chamada de. PDF | Essential oils produced from leaves of Astronium fraxinifolium Schott. harvested at four different stages of maturity have been analyzed by GC/MS.

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Leishmania amazonensisand L.

Astronium fraxinifolium – Dictionary Definition :

Ethanolic extracts from A. Astornium, golden hamsters were infected s. Another problem is related to the lower efficacy of the drugs in children compared to adults fraxinifolum 11 ]. Nonetheless, we decided to test the EOPA treatment in animal models based on data from other researchers [ 33 ] who showed a good antileishmanial activity of essential oil, in the case of Lippia sidoides Cham. The data relating to the parasite load were analyzed using the nonparametric Mann-Whitney test.

On the other hand, all the ethanolic extracts from bark, sapwood, and leaves from A. If you have any useful information about this plant, please leave a comment. The Myracrodruon urundeuva species, a plant of the same family, native in northeastern Brazil, is widely used in folk medicine for treatment of various dermatological disorders and is known to have antimicrobial [ 19 ], antiulcer [ 20 ], and anti-inflammatory activities [ 21 ].

Treatment with Ethanolic Extracts of Leaves from A. Parasite Load The number of parasites in the lesions was quantified by the limiting dilution technique as previously described [ 30 ]. The authors declare that there is no conflict of interests regarding the publication of this paper.

The analyses were performed using GraphPad Prism version 5. The treatment was initiated when the lesions appeared about the 27th day. The parasites were fixed in formaldehyde, stained with Trypan blue and visualized at light microscope at x magnification.


The parasites were counted in a Neubauer chamber. The animals were treated with leaf ethanolic extract from Astronium fraxinifolium EEF. Looking into the canopy Photograph by: In vitro results showed that both essential oil of P.

Furthermore, the continuous use of ineffective drugs has led to the development of resistance to their compounds [ 16 ], which have stirred an urgent need for novel, effective, and safe drugs for treatment of leishmaniasis.

Fruiting branch Photograph by: According to the World of Health Organization [ 2 ], about 0. In general, these compounds are also expensive and require long-term treatment [ 8 ].

fraxibifolium Tropical Plants Database, Ken Fern. The major component of the essential oil was carvacrol. In Vitro Studies 2. No difference was found in lesion thickness when those animals were compared with the untreated animals.

Introduction Leishmaniasis is a disease that affects human beings and animals and is caused by the protozoa parasite of the genus Leishmania which is transmitted by the bite of infected female phlebotomine sandflies and displays a spectrum of manifestations which goes from cutaneous involvement CL with late destruction of mucous membranes to generalized systemic visceral disease VL with fatal outcome if not treated [ 1 ].

The number of parasites in the lesions was quantified by the limiting dilution technique as previously described [ 30 ]. The treatment was initiated when the lesions appeared about the 20th day after infection.

Astronium fraxinifolium Images – Useful Tropical Plants

Lesion thickness a and number of parasites b in hamster footpad infected astronjum 10 6 promastigotes of Leishmania braziliensis. For the in vitro tests, essential oil of P. Various factors contribute to the increase of the disease incidence, for instance, the process of urbanization which alters the environment in decurrence of economic and social pressures [ 5 ].


View at Google Scholar E. Astdonium, we decided to use the gold hamster model to evaluate the activity of our plant materials in vivo based on the fact that hamsters are known to be highly susceptible to Leishmania subgenus Viannia infection [ 35 ].

One hundred microliters of these dilutions was distributed wstronium well flat bottom plates containing agar-blood in 6 replicates per concentration. Also, male animals were tested because this gender is more susceptible to the Leishmania infection than the females, and this susceptibility seems to be related to the type of cytokine produced [ 35 ]. In conclusion, both essential oil from P. Stunning photographs of each species, brief details on the plant, its uses and atronium to grow it from seed.

However, a higher number of parasites were found when the group of animals treated with the plant material was compared with the group treated with Glucantime.

BioMed Research International

Its activities are poorly known unlike the other plant from the same family, M. After the 7th week of infection, the lesion asrronium in the group treated with the plant material was below the limit of normal thickness. Cytotoxicity of the plant material. Viannia braziliensisL. Alternatively, pentamidine and amphotericin B may be used.

The ethanolic extracts of the bark, sapwood, and leaves of A. To receive fraxibifolium and publication updates for BioMed Research International, enter your email address in the box below. According to their data, mice infected with L. Sierra Romero, and Z.

Antileishmanial Evaluation The in vitro evaluation of the antileishmanial activity of the essential oil from P. Parasites The strain of L.