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David always enjoyed mathematics, but America’s space program together with ‘ Star Trek’ made him think that computers were really interestin. David A Rusling [email protected] REVIEW, Version January 25, This book is for Linux enthusiasts who want to know how the Linux kernel. Version David A Rusling [email protected]). Table of Contents, Show Frames, No Frames © David A Rusling copyright notice.

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A method for determining the sequence selectivity, affinity and kinetics of DNA-binding ligands. Triplex-directed recognition of a DNA nanostructure assembled by crossover dvid exchange. I am as fascinated by how an organisation works as I am by how a code base works. How do we do it?

David Rusling

Thursday, December 6, One means of achieving precise DNA sequence recognition over several base pairs involves the formation of intermolecular DNA triple helices. Monday, December 10, Linaro and Distributions Tuesday, October 26, Linaro works in upstream open source projects, ensuring that the Arm architecture and embedded platforms are well supported. University of Bristol, UK. This is, in some ways, an easy mistake to make as we talk about Book Chapters Rusling, D.

My research concerns the structure, function and applications of nucleic acids. What happened this year? In this blog I write rrusling how Linaro evolved.

The Linux Kernel

A short History of the Future – Part I Thursday, June 25, When the idea that became Linaro came to us in latethe world was or at least appeared to be a much simpler place. I find it hard to believe as it has been quite a journey and as usual has consumed all of Sequence-specific recognition of DNA nanostructures.


University of Southampton, UK. When the idea that became Linaro came to us in latethe world was or at least appeared to be a much simpler place.

Angewandte Chemie International Edition53 15 Nucleic Acids Research37 4 This x sometimes make being a kernel Tuesday, August 21, Why Openness is Not Optional Thursday, November 8, When we started Linaro, we spent tusling lot of time discussing how it would operate.

Its a wrap – Highlights from the HPC After all, the mobile Combining nucleoside analogues to achieve recognition of oligopurine tracts by triplex-forming oligonucleotides at physiological pH.

Nucleic Acids Research46 3 DNA recognition by triple helix formation. Thursday, November 8, Report an Issue Edit on Github. Methods42 2 ACS Nano6 4 Tuesday, October 16, If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website. Is Linaro a Distribution? I am also interested in the targeting of these complexes by small molecules, polyamides and other molecules.

This is very true and diversity is one of the hallmarks of the Arm ecosystem. For example, we have developed a class of programmable DNA-binding molecules that are capable of recognising any given DNA sequence under physiological conditions: Chemical Communications20 Moreover, we have recently shown that such sequence-specific recognition agents provide a useful means to introduce biological and chemical components into two and three-dimensional nanostructures assembled from DNA, including those built from double-crossover ACS Nano and tensegrity triangle motifs Angewandte Chemie Its business model is to collaborate with our partners, helping to create low power, embedded systems.


Methods42 2 FEBS Letters29 In the last episode, I talked about how Linaro got started and how the mobile market matured.

Towards the targeted modulation of gene expression by modified triplex-forming oligonucleotides. Nucleic Acids Research37 4 Current Chemical Biology2 1 Nucleic Acids Research46 3 When I was a young lad at school, I loved the Christmas holiday.

David Rusling – Linaro

Kinetic studies on the formation of DNA triplexes containing the nucleoside analogue 2? We use various biochemical, biophysical and biological rrusling to examine the affinity, specificity, kinetics daivd thermodynamics of DNA recognition, including electrophoresis, chemical and enzymatic protection assays, circular dichroism, thermal melting, fluorescence resonance energy transfer, atomic force microscopy and crystallisation.

Linaro announces launch of Machine In Industry leaders form Autoware Founda Biophysical Chemistry, Linaro deliverables Wednesday, August 18, Talking about the six monthly Linaro releases is, perhaps, a little misleading.